Professor Kerry-Anne Rye BSc (Hons) PhD

Kerry-Anne Rye is a conjoint Professor in the Faculty of Medicine, University of Sydney, Australia and Associate Director and Head of the Lipid Research Group, Heart Research Institute, Sydney, Australia. She is an internationally recognized expert on high-density lipoprotein (HDL) metabolism and how HDL affect diabetes, atherosclerosis and inflammatory processes.

Over the last 15 years Professor Rye has pioneered the use of reconstituted HDL to investigate the re-modelling and anti-inflammatory properties of this lipoprotein class. These studies have led to major advances in understanding the metabolism of different types of HDL, and the regulation of their anti-inflammatory properties.

Professor Rye has published more than 100 papers and book chapters on these topics. She has given invited presentations and keynote addresses on various aspects of HDL metabolism at numerous meetings including the Scientific Sessions of the American Heart Association, the European Atherosclerosis Society, the Atherosclerosis, Thrombosis and Vascular Biology Council Meetings of the American Heart Association, International Atherosclerosis-Society–sponsored Workshops and Satellite Meetings of the International Symposium on Atherosclerosis.

Professor Rye obtained her PhD from the Flinders University of South Australia, followed by post-doctoral training at the University of Illinois, Urbana Champaign. She subsequently joined the Heart Research Institute in 2001.


Most recent publications include:

Barter P, Puranik R, Rye KA. New Insights into the role of HDL as an anti-inflammatory agent in the prevention of cardiovascular disease. Curr Cardiol Rep 2007;9:493-8. www.ncbi.nlm.nih.gov/sites/entrez

Caiazza D, Jahangiri A, Rader DJ, Marchadier D, Rye KA. Apolipoproteins regulate the kinetics of endothelial lipase-mediated hydrolysis of phospholipids in reconstituted highdensity lipoproteins. Biochemistry 2004;43:11898-905.
www.ncbi.nlm.nih.gov/sites/entrez


Most cited publications include:

Caiazza D, Jahangiri A, Rader DJ, Marchadier D, Rye KA. Apolipoproteins regulate the kinetics of endothelial lipase-mediated hydrolysis of phospholipids in reconstituted highdensity lipoproteins. Biochemistry 2004;43:11898-905.
www.ncbi.nlm.nih.gov/sites/entrez

Rye KA, Barter PJ. Formation and metabolism of prebeta-migrating, lipid-poor apolipoprotein A-I. Arterioscler Thromb Vasc Biol 2004;24:421-8.
www.ncbi.nlm.nih.gov/sites/entrez

BRye KA, Wee K, Curtiss LK, Bonnet DJ, Barter PJ. Apolipoprotein A-II inhibits high density lipoprotein remodeling and lipid-poor apolipoprotein A-I formation. J Biol Chem 2003;278:22530-6.